CTPS2 (NM_001144002) Human Untagged Clone

CAT#: SC325216

CTPS2 (untagged)-Human CTP synthase II (CTPS2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CTPS2
• Synonyms: DKFZp686C17207; FLJ43358; MGC32997
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001144002, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGTACATCCTGGTCACGGGTGGGGTCATCTCAGGCATTGGTAAAGGGATCATTGCCAGCAGCATTG
  GAACGATTCTAAAATCATGTGGACTCCGAGTTACTGCCATAAAAATCGACCCCTATATTAACATCGATGC
  TGGCACTTTTTCACCTTATGAACACGGTGAAGTCTTCGTCTTAAATGATGGTGGAGAAGTTGATTTAGAC
  CTTGGAAATTATGAAAGATTTTTGGATATTAATCTTTATAAAGACAACAATATCACCACGGGGAAGATAT
  ATCAGCATGTGATCAATAAAGAGAGGCGTGGTGATTACCTGGGGAAAACAGTGCAAGTTGTCCCTCACAT
  TACTGATGCTGTCCAGGAGTGGGTTATGAATCAAGCCAAGGTGCCGGTGGATGGTAATAAGGAAGAGCCC
  CAAATATGCGTTATTGAGCTGGGAGGCACCATTGGAGACATCGAAGGAATGCCGTTTGTGGAGGCGTTTA
  GACAATTCCAGTTTAAGGCGAAAAGAGAGAATTTCTGTAATATCCACGTTAGCCTTGTCCCACAGCTCAG
  TGCTACCGGAGAACAAAAAACCAAACCCACCCAAAACAGCGTCCGCGCACTGAGGGGTTTAGGCCTGTCT
  CCAGATCTGATTGTCTGCCGAAGTTCAACGCCCATTGAGATGGCCGTGAAGGAGAAGATTTCTATGTTTT
  GTCACGTGAACCCTGAACAGGTCATATGTATCCATGATGTTTCTTCCACATACCGAGTTCCTGTGCTTTT
  AGAGGAACAAAGCATTGTGAAATATTTTAAGGAGAGATTGCACCTGCCCATCGGTGATTCTGCAAGTAAT
  TTGCTTTTTAAGTGGAGAAATATGGCTGACAGGTATGAAAGGTTACAGAAAATATGCTCCATAGCCCTGG
  TTGGCAAATACACCAAGCTCAGAGACTGCTACGCCTCTGTGTTCAAAGCCCTGGAACACTCAGCCCTGGC
  CATCAACCACAAGTTGAATCTGATGTACATAGACTCCATTGATCTGGAGAAGATCACTGAAACCGAGGAC
  CCTGTGAAATTTCATGAAGCTTGGCAGAAGCTATGCAAAGCTGATGGTATTCTTGTGCCTGGAGGCTTTG
  GAATCAGAGGAACATTGGGAAAACTCCAGGCGATTTCTTGGGCAAGGACAAAGAAGATTCCTTTTCTGGG
  AGTTTGTCTTGGGATGCAACTAGCAGTGATAGAGTTTGCAAGAAACTGCCTTAACTTGAAAGATGCTGAT
  TCCACAGAGTTTAGGCCAAATGCCCCAGTTCCTCTGGTGATTGATATGCCCGAGCACAACCCTGGCAATT
  TGGGAGGAACAATGAGACTGGGAATAAGAAGAACTGTTTTCAAAACTGAAAATTCAATATTAAGGAAACT
  TTATGGTGATGTTCCTTTTATAGAAGAAAGACACAGACATCGGTTCGAGGTAAACCCTAACCTGATCAAA
  CAATTTGAGCAGAATGACTTAAGTTTTGTAGGTCAGGATGTTGATGGAGACAGGATGGAAATCATTGAAC
  TGGCAAATCATCCTTATTTTGTTGGTGTCCAGTTCCATCCTGAGTTTTCTTCTAGGCCGATGAAGCCTTC
  CCCTCCGTATCTGGGGCTGTTACTTGCAGCAACTGGGAACCTGAATGCCTACTTGCAACAGGGTTGCAAA
  CTGTCTTCCAGTGATAGATACAGTGATGCCAGTGATGACAGCTTTTCAGAGCCAAGGATAGCTGAGTTGG
  AAATAAGCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001144002
• ORF Size: 1761 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001144002.1, NP_001137474.1
• RefSeq Size: 4334
• RefSeq ORF: 1761
• Locus ID: 56474
• Protein Pathways: Metabolic pathways, Pyrimidine metabolism
• Gene Summary: The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (3) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.