ABI3 (NM_001135186) Human Untagged Clone

CAT#: SC325821

ABI3 (untagged)-Human ABI family, member 3 (ABI3), transcript variant 2


  "NM_001135186" in other vectors (4)

Reconstitution Protocol

USD 610.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ABI3
Synonyms NESH; SSH3BP3
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>NCBI ORF sequence for NM_001135186, the custom clone sequence may differ by one or more nucleotides


ATGGCGGAGCTACAGCAGCTGCAGGAGTTTGAGATCCCCACTGGCCGGGAGGCTCTGAGGGGCAACCACA
GTGCCCTGCTGCGGGTCGCTGACTACTGCGAGGACAACTATGTGCAGGCCACAGACAAGCGGAAGGCGCT
GGAGGAGACCATGGCCTTCACTACCCAGGCACTGGCCAGCGTGGCCTACCAGGTGGGCAACCTGGCCGGG
CACACTCTGCGCATGTTGGACCTGCAGGGGGCCGCCCTGCGGCAGGTGGAAGCCCGTATGGTGAACATGC
ATATGGAGAAGGTGGCCCGAAGGGAGATCGGCACCTTAGCCACTGTCCAGCGGCTGCCCCCCGGCCAGAA
GGTCATCGCCCCAGAGAACCTACCCCCTCTCACGCCCTACTGCAGGAGACCCCTCAACTTTGGCTGCCTG
GACGACATTGGCCATGGGATCAAGGACCTCAGCACGCAGCTGTCAAGAACAGGCACCCTGTCTCGAAAGA
GCATCAAGGCCCCTGCCACACCCGCCTCCGCCACCTTGGGGAGACCACCCCGGATTCCCGAGCCAGTGCA
CCTGCCGGTGGTGCCCGACGGCAGACTCTCCGCCGCCTCCTCTGCGTCTTCCCTGGCCTCGGCCGGCAGC
GCCGAAGGTGTCGGTGGGGCCCCCACGCCCAAGGGGCAGGCAGCACCTCCAGCCCCACCTCTCCCCAGCT
CCTTGGACCCACCTCCTCCACCAGCAGCCGTCGAGGTGTTCCAGCGGCCTCCCACGCTGGAGGAGTTGTC
CCCACCCCCACCGGACGAAGAGCTGCCCCTGCCACTGGACCTGCCTCCTCCTCCACCCCTGGATGGAGAT
GAATTGGGGCTGCCTCCACCCCCACCAGGATTTGGGCCTGATGAGCCCAGCTGGGTGCCTGCCTCATACT
TGGAGAAAGTGGTGACACTGTACCCATACACCAGCCAGAAGGACAATGAGCTCTCCTTCTCTGAGGGCAC
TGTCATCTGTGTCACTCGCCGCTACTCCGATGGCTGGTGCGAGGGCGTCAGCTCAGAGGGGACTGGATTC
TTCCCTGGGAACTATGTGGAGCCCAGCTGCTGA


Restriction Sites SgfI-MluI     
ACCN NM_001135186
ORF Size 1083 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_001135186.1, NP_001128658.1
RefSeq Size 2111
RefSeq ORF 1083
Locus ID 51225
Gene Summary This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2).

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