ASB10 (NM_001142460) Human Untagged Clone

CAT#: SC325974

ASB10 (untagged)-Human ankyrin repeat and SOCS box containing 10 (ASB10), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ASB10
• Synonyms: GLC1F
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001142460, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTCATGAGTTGGTCTCCAGAAGAGTGCAAGGGGCAGGGAGAGCCCCTCGATGACAGACACCCCCTCT
  GTGCCAGGCTGGTGGAGAAGCCCAGCAGAGGGTCTGAGGAGCACCTCAAGTCTGGCCCGGGACCCATCGT
  CACCCGCACAGCCTCAGGACCTGCCCTTGCCTTCTGGCAGGCAGTGCTGGCTGGGGACGTGGGCTGTGTC
  TCCCGCATCCTCGCGGACTCCAGTACTGGCCTGGCTCCTGATTCCGTCTTTGATACCAGCGACCCAGAGC
  GATGGAGGGATTTCCGCTTCAACATCCGTGCTCTGAGACTCTGGTCTCTGACATACGAAGAGGAGCTGAC
  CACCCCACTGCATGTGGCAGCCAGCCGTGGCCACACGGAAGTCCTGCGGCTGCTGCTGAGGCGGCGAGCA
  AGGCCAGACAGTGCCCCTGGGGGCCGCACCGCCCTGCACGAGGCCTGTGCTGCAGGCCACACTGCCTGTG
  TTCATGTGCTGCTGGTGGCAGGAGCCGACCCCAACATCGCTGACCAGGATGGGAAACGCCCCCTGCATCT
  CTGCCGGGGGCCTGGCACCCTTGAGTGTGCGGAGCTGCTCCTCAGGTTTGGAGCGAGAGTGGATGGTCGG
  TCCGAGGAAGAAGAGGAGACCCCTTTGCATGTGGCCGCCCGGCTTGGCCATGTGGAGCTGGCAGATCTGC
  TTCTAAGACGGGGGGCATGTCCTGATGCCCGCAATGCCGAAGGCTGGACCCCACTGCTGGCTGCCTGTGA
  CGTCCGCTGCCAGTCCATCACCGATGCCGAGGCCACCACCGCCCGCTGCCTGCAGCTGTGCAGCTTGCTG
  CTTTCAGCTGGAGCAGACGCTGATGCTGCGGACCAGGACAAGCAGCGACCCCTGCACCTGGCCTGCCGCC
  GTGGCCATGCAGCTGTCGTGGAGCTGCTCCTGTCCTGTGGTGTCAGCGCCAACACCATGGACTATGGGGG
  ACACACGCCCCTGCACTGTGCTCTGCAGGGCCCAGCTGCAGCCCTGGCCCAGAGCCCCGAGCACGTGGTT
  CGGGCTCTGCTCAACCATGGCGCCGTCCGTGTCTGGCCAGGGGCCCTCCCCAAGAAACATCAGCGTTTCT
  ACTCCTCCCTCTTCGCCTTGGTGAGGCAGCCCAGGTCGCTGCAGCATTTGAGCCGCTGTGCGCTCCGCTC
  CCACCTGGAGGGCAGCCTGCCCCAAGCGCTGCCCCGCCTCCCCCTGCCACCGCGCCTGCTCCGCTACCTG
  CAGCTGGATTTTGAGGGCGTGCTCTACTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001142460
• ORF Size: 1290 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001142460.1, NP_001135932.2
• RefSeq Size: 1820
• RefSeq ORF: 1290
• Locus ID: 136371
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1. The transcript contains an in-frame start site 45 codons upstream from the currently annotated site. The annotated downstream AUG is better conserved and has a strong Kozak signal.