HBS1L (NM_001145158) Human Untagged Clone

CAT#: SC326142

HBS1L (untagged)-Human HBS1-like (S. cerevisiae) (HBS1L), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HBS1L
• Synonyms: EF-1a; eRF3c; ERFS; HBS1; HSPC276
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001145158, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCCGGCATCGGAATGTTCGAGGCTATAACTACGATGAAGATTTTGAAGATGATGATCTCTACGGCC
  AGTCTGTAGAGGATGATTATTGTATTTCGCCGTCAACAGCTCGTCTTTATTCATGCCTTGATCACATGAG
  AGAGGTACTTGGAGATGCTGTGCCAGATGAAATATTAATTGAAGCAGTTCTGAAGAACAAGTTTGATGTG
  CAGAAGGCTTTGTCAGGGGTTCTGGAACAAGATAGAGTGCAGAGTTTGAAGGACAAGAATGAGGCAACAG
  TATCTACAGGAAAGATAGCAAAAGGAAAACCAGTAGATTCCCAGACATCGCGAAGTGAATCTGAAATTGT
  GCCAAAAGTTGCTAAAATGACTGTATCTGGAAAGAAGCAAACTATGGGATTTGAAGTGCCTGGAGTATCT
  TCTGAAGAAAATGGTCATAGTTTCCACACACCTCAAAAAGGACCGCCCATTGAAGATGCCATTGCTTCTT
  CCGATGTTCTTGAGACTGCTTCTAAATCTGCTAATCCACCCCACACGATTCAAGCATCAGAAGAGCAGAG
  TTCAACCCCAGCACCGGTGAAAAAGTCTGGCAAGCTGAGGCAGCAAATAGATGTGAAGGCGGAACTGGAG
  AAGCGGCAAGGAGGGAAGCAGCTACTCAACTTAGTGGTCATTGGTCATGTTGATGCTGGGAAAAGTACTC
  TGATGGGCCATATGCTTTATCTTCTGGGTAATATAAACAAAAGAACTATGCATAAGTATGAACAGGAGTC
  TAAAAAGGCTGGCAAAGCTTCGTTTGCATATGCATGGGTCTTGGATGAAACTGGCGAAGAAAGGGAAAGG
  GGAGTAACCATGGATGTTGGTATGACAAAGTTTGAAACCACAACCAAAGTTATTACATTAATGGATGCTC
  CAGGCCATAAGGACTTCATTCCAAATATGATTACAGGAGCAGCCCAGGCGGATGTAGCTGTTTTAGTTGT
  AGATGCCAGCAGGGGAGAGTTTGAAGCTGGATTTGAGACTGGAGGACAAACACGAGAGCATGGACTCTTG
  GTCCGTTCTCTGGGAGTGACGCAGCTTGCAGTTGCAGTTAATAAAATGGATCAGGTTAATTGGCAACAAG
  AAAGGTTTCAAGAGATTACTGGAAAACTTGGGCACTTTCTTAAGCAAGCAGGTTTTAAGGAGAGTGATGT
  AGGTTTTATTCCTACAAGTGGTCTCAGTGGTGAAAATCTAATCACAAGATCTCAGTCAAGTGAACTCACA
  AAATGGTATAAAGGACTATGTTTATTAGAACAAATTGATTCCTTTAAGCCTCCCCAGCGATCTATTGACA
  AACCTTTTAGATTATGTGTGTCCGATGTTTTCAAAGATCAAGGATCTGGATTTTGCATAACTGGTAAAAT
  AGAAGCTGGTTATATCCAAACTGGTGACCGACTACTGGCAATGCCTCCTAATGAAACTTGTACCGTGAAA
  GGAATCACTCTGCATGATGAACCTGTCGACTGGGCGGCAGCAGGCGATCATGTTAGTCTTACTTTGGTTG
  GGATGGATATCATCAAAATCAATGTTGGCTGCATATTTTGTGGCCCCAAAGTACCCATTAAAGCTTGCAC
  TCGTTTCAGAGCCCGAATCCTCATCTTTAATATTGAAATTCCTATCACTAAAGGATTTCCTGTGCTGTTA
  CACTACCAAACTGTCAGTGAACCCGCCGTTATTAAACGATTGATTAGTGTCTTAAACAAAAGCACGGGTG
  AAGTCACAAAGAAAAAGCCTAAGTTTTTGACTAAAGGCCAGAATGCATTGGTAGAGCTACAGACACAAAG
  ACCAATAGCTCTTGAGCTATATAAAGACTTTAAAGAGCTGGGGAGGTTCATGCTACGTTACGGTGGTTCT
  ACAATAGCTGCTGGTGTTGTCACTGAGATAAAAGAATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001145158
• ORF Size: 1929 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001145158.1, NP_001138630.1
• RefSeq Size: 7037
• RefSeq ORF: 1929
• Locus ID: 10767
• Gene Summary: This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009]
  Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. This results in a shorter protein (isoform 2) compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.