SIGLEC10 (NM_001171161) Human Untagged Clone

CAT#: SC328749

SIGLEC10 (untagged)-Human sialic acid binding Ig-like lectin 10 (SIGLEC10) transcript variant 7

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SIGLEC10
• Synonyms: PRO940; SIGLEC-10; SLG2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001171161, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTACTGCCACTGCTGCTGTCCTCGCTGCTGGGCGGGTCCCAGGCTATGGATGGGAGATTCTGGATAC
  GAGTGCAGGAGTCAGTGATGGTGCCGGAGGGCCTGTGCATCTCTGTGCCCTGCTCTTTCTCCTACCCCCG
  ACAAGACTGGACAGGGTCTACCCCAGCTTATGGCTACTGGTTCAAAGCAGTGACTGAGACAACCAAGGGT
  GCTCCTGTGGCCACAAACCACCAGAGTCGAGAGGTGGAAATGAGCACCCGGGGCCGATTCCAGCTCACTG
  GGGATCCCGCCAAGGGGAACTGCTCCTTGGTGATCAGAGACGCGCAGATGCAGGATGAGTCACAGTACTT
  CTTTCGGGTGGAGAGAGGAAGCTATGTGAGATATAATTTCATGAACGATGGGTTCTTTCTAAAAGTAACA
  GTGCTCAGCTTCACGCCCAGACCCCAGGACCACAACACCGACCTCACCTGCCATGTGGACTTCTCCAGAA
  AGGGTGTGAGCGCACAGAGGACCGTCCGACTCCGTGTGGCCTATGCCCCCAGAGACCTTGTTATCAGCAT
  TTCACGTGACAACACGCCAGATCCTCCAGAGAACCTGAGAGTGATGGTTTCCCAAGCAAACAGGACAGTC
  CTGGAAAACCTTGGGAACGGCACGTCTCTCCCAGTACTGGAGGGCCAAAGCCTGTGCCTGGTCTGTGTCA
  CACACAGCAGCCCCCCAGCCAGGCTGAGCTGGACCCAGAGGGGACAGGTTCTGAGCCCCTCCCAGCCCTC
  AGACCCCGGGGTCCTGGAGCTGCCTCGGGTTCAAGTGGAGCACGAAGGAGAGTTCACCTGCCACGCTCGG
  CACCCACTGGGCTCCCAGCACGTCTCTCTCAGCCTCTCCGTGCACTATAAGAAGGGACTCATCTCAACGG
  CATTCTCCAACGGAGCGTTTCTGGGAATCGGCATCACGGCTCTTCTTTTCCTCTGCCTGGCCCTGATCAT
  CATGAAGATTCTACCGAAGAGACGGACTCAGACAGAAACCCCGAGGCCCAGGTTCTCCCGGCACAGCACG
  ATCCTGGATTACATCAATGTGGTCCCGACGGCTGGCCCCCTGGCTCAGAAGCGGAATCAGAAAGCCACAC
  CAAACAGTCCTCGGACCCCTCTTCCACCAGGTGCTCCCTCCCCAGAATCAAAGAAGAACCAGAAAAAGCA
  GTATCAGTTGCCCAGTTTCCCAGAACCCAAATCATCCACTCAAGCCCCAGAATCCCAGGAGAGCCAAGAG
  GAGCTCCATTATGCCACGCTCAACTTCCCAGGCGTCAGACCCAGGCCTGAGGCCCGGATGCCCAAGGGCA
  CCCAGGCGGATTATGCAGAAGTCAAGTTCCAATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001171161
• ORF Size: 1365 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001171161.1, NP_001164632.1
• RefSeq Size: 2671
• RefSeq ORF: 1365
• Locus ID: 89790
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405). [supplied by OMIM, Jul 2002]
  Transcript Variant: This variant (7) lacks an in-frame segment and two in-frame exons in the CDS, as compared to variant 1. The resulting isoform (7) lacks three internal segments, as compared to isoform 1.