IL16 (NM_001172128) Human Untagged Clone

CAT#: SC329340

IL16 (untagged)-Human interleukin 16 (lymphocyte chemoattractant factor) (IL16) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL16
• Synonyms: LCF; NIL16; prIL-16; PRIL16
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001172128, the custom clone sequence may differ by one or more nucleotides
  ATGGAGTCGCACAGCCGCGCTGGAAAGAGCAGAAAATCTGCAAAATTTCGGTCCATCTCC
  AGGTCCCTGATGCTCTGTAATGCTAAGACCAGTGATGATGGCTCTAGCCCTGATGAGAAA
  TATCCTGATCCCTTTGAGATTTCCTTGGCCCAGGGCAAGGAGGGAATTTTCCACTCATCT
  GTGCAGCTGGCAGACACATCGGAGGCTGGGCCCAGCAGTGTTCCTGATCTAGCACTGGCC
  TCGGAGGCTGCTCAACTCCAAGCAGCTGGGAATGATCGAGGCAAGACCTGTAGGAGGATA
  TTCTTCATGAAGGAATCTTCCACAGCTTCCTCTCGAGAAAAGCCTGGAAAACTAGAAGCA
  CAAAGTAGTAACTTCCTGTTTCCTAAAGCCTGCCACCAAAGGGCACGCAGCAACTCAACC
  AGTGTTAATCCCTATTGCACAAGAGAAATTGATTTTCCAATGACCAAGAAATCTGCAGCG
  CCCACGGACAGGCAGCCTTACTCTCTCTGCAGTAACAGGAAGTCCCTCTCTCAACAATTG
  GACTGTCCAGCAGGAAAGGCTGCGGGAACTTCGAGACCAACACGGTCCCTGAGCACAGCT
  CAGCTCGTGCAGCCATCTGGGGGCCTCCAGGCTTCAGTCATCTCCAACATCGTGCTGATG
  AAGGGCCAGGCTAAGGGTCTGGGCTTCAGCATCGTTGGGGGAAAAGACAGCATTTATGGC
  CCCATTGGGATTTACGTCAAAACCATTTTTGCAGGGGGAGCAGCAGCAGCCGATGGAAGG
  CTACAGGAAGGTGATGAAATTCTGGAGCTCAATGGTGAATCAATGGCTGGACTAACACAT
  CAGGATGCTTTGCAGAAGTTCAAGCAAGCCAAAAAGGGGCTCCTCACCCTCACCGTGAGA
  ACCCGCCTGACGGCGCCTCCTTCCCTGTGCAGCCACCTGTCTCCCCCACTGTGCCGCTCC
  CTGAGCTCCAGCACTTGTATCACCAAGGACAGCAGCTCCTTCGCCTTGGAAAGCCCCTCG
  GCTCCCATCAGCACCGCCAAGCCCAATTACAGAATCATGGTGGAGGTTTCTCTGCAGAAA
  GAGGCCGGCGTGGGCCTGGGCATCGGCCTGTGCAGCGTTCCCTACTTCCAATGCATCTCT
  GGCATTTTCGTCCACACGCTGTCACCAGGATCCGTGGCGCACCTGGACGGACGTCTCCGG
  TGTGGGGACGAGATTGTGGAAATCAGTGATTCCCCTGTGCACTGCCTGACGCTCAATGAA
  GTCTACACGATCCTGAGTCACTGTGATCCCGGTCCAGTCCCCATCATTGTTAGCCGACAT
  CCAGACCCACAGGTCTCTGAACAGCAACTCAAAGAAGCTGTGGCCCAGGCTGTGGAAAAC
  ACCAAGTTTGGAAAGGAGAGGCATCAGTGGAGTCTGGAAGGTGTCAAAAGGCTGGAAAGC
  AGTTGGCACGGGCGGCCCACCTTGGAGAAGGAACGAGAGAAGAACTCAGCACCCCCGCAT
  CGCAGGGCTCAGAAGGTCATGATCCGCTCCAGCAGTGACAGCAGCTACATGTCTGGGTCC
  CCAGGGGGAAGTCCTGGGAGTGGCAGTGCTGAGAAGCCGTCCTCTGACGTGGACATCAGC
  ACACACAGCCCCAGCTTGCCTCTGGCACGGGAGCCAGTGGTGCTTTCTATAGCATCCTCC
  AGGCTGCCCCAGGAGAGCCCACCCCTCCCAGAGAGCCGGGACAGCCACCCGCCGCTGAGA
  CTGAAGAAATCCTTTGAGATTTTGGTGAGAAAGCCTATGTCCTCCAAGCCCAAGCCTCCA
  CCCAGAAAATACTTTAAAAGTGACAGTGACCCTCAGAAGAGTCTGGAAGAGAGAGAGAAC
  TCCTCATGCTCTTCTGGGCACACCCCACCCACCTGTGGCCAGGAAGCGAGAGAGCTGCTG
  CCACTGCTGCTACCACAGGAAGACACAGCAGGGAGAAGCCCTAGTGCCTCTGCCGGCTGC
  CCAGGACCTGGTATCGGCCCACAGACCAAGTCCTCCACAGAGGGCGAGCCAGGGTGGAGA
  AGAGCCAGCCCAGTGACCCAAACATCCCCGATAAAACACCCACTGCTTAAGAGGCAGGCT
  CGGATGGACTATAGCTTTGATACCACAGCCGAAGACCCTTGGGTTAGGATTTCTGACTGC
  ATCAAAAACTTATTTAGCCCCATCATGAGTGAGAACCATGGCCACATGCCTCTACAGCCC
  AATGCCAGCCTGAATGAAGAAGAAGGGACACAGGGCCACCCAGATGGGACCCCACCAAAG
  CTGGACACCGCCAATGGCACTCCCAAAGTTTACAAGTCAGCAGACAGCAGCACTGTGAAG
  AAAGGTCCTCCTGTGGCTCCCAAGCCAGCCTGGTTTCGCCAAAGCTTGAAAGGTTTGAGG
  AATCGTGCTTCAGACCCAAGAGGGCTCCCTGATCCTGCCTTGTCCACCCAGCCAGCACCT
  GCTTCCAGGGAGCACCTAGGATCACACATCCGGGCCTCCTCCTCCTCCTCCTCCATCAGG
  CAGAGAATCAGCTCCTTTGAAACCTTTGGCTCCTCTCAACTGCCTGACAAAGGAGCCCAG
  AGACTGAGCCTCCAGCCCTCCTCTGGGGAGGCAGCAAAACCTCTTGGGAAGCATGAGGAA
  GGACGGTTTTCTGGACTCTTGGGGCGAGGGGCTGCACCCACTCTTGTGCCCCAGCAGCCT
  GAGCAAGTACTGTCCTCGGGGTCCCCTGCAGCCTCCGAGGCCAGAGACCCAGGTGTGTCT
  GAGTCCCCTCCCCCAGGGCGGCAGCCCAATCAGAAAACTCTCCCCCCTGGCCCGGACCCG
  CTCCTAAGGCTGCTGTCAACACAGGCTGAGGAATCTCAAGGCCCAGTGCTCAAGATGCCT
  AGCCAGCGAGCACGGAGCTTCCCCCTGACCAGGTCCCAGTCCTGTGAGACGAAGCTACTT
  GACGAAAAGACCAGCAAACTCTATTCTATCAGCAGCCAAGTGTCATCGGCTGTCATGAAA
  TCCTTGCTGTGCCTTCCATCTTCTATCTCCTGTGCCCAGACTCCCTGCATCCCCAAGGAA
  GGGGCATCTCCAACATCATCATCCAACGAAGACTCAGCTGCAAATGGTTCTGCTGAAACA
  TCTGCCTTGGACACAGGGTTCTCGCTCAACCTTTCAGAGCTGAGAGAATATACAGAGGGT
  CTCACGGAAGCCAAGGAAGACGATGATGGGGACCACAGTTCCCTTCAGTCTGGTCAGTCC
  GTTATCTCCCTGCTGAGCTCAGAAGAATTAAAAAAACTCATCGAGGAGGTGAAGGTTCTG
  GATGAAGCAACATTAAAGCAATTAGACGGCATCCATGTCACCATCTTACACAAGGAGGAA
  GGTGCTGGTCTTGGGTTCAGCTTGGCAGGAGGAGCAGATCTAGAAAACAAGGTGATTACG
  GTTCACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAAT
  GAGGTTCTTTCCATCAACGGCAAGTCTCTCAAGGGGACCACGCACCATGATGCCTTGGCC
  ATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACTCCA
  GAGGCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGT
  GATGTTTCTGTAGAATCTACAGAGGCCACAGTCTGCACGGTGACACTGGAGAAGATGTCG
  GCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAGCCTCTC
  ACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGA
  GATGAAATCTTGCAGCTGGGTGGCACTGCCATGCAGGGCCTCACACGGTTTGAAGCCTGG
  AACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAAAGCCTC
  CAGTCCAAGGAAACCACAGCTGCTGGAGACTCCTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001172128
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001172128.1, NP_001165599.1
• RefSeq Size: 8322 bp
• RefSeq ORF: 3996 bp
• Locus ID: 3603
• Cytogenetics: 15q25.1
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: 'The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]'
  Transcript Variant: This variant (3) has multiple differences and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) is longer, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.