UGT2A1 (NM_001252275) Human Untagged Clone

CAT#: SC330282

UGT2A1 (untagged) - Homo sapiens UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus (UGT2A1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UGT2A1
• Synonyms: UDPGT2A1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001252275, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTAAACAACCTTCTGCTGTTCTCCCTTCAGATAAGTCTCATAGGAACCACTCTTGGTGGGAATGTTT
  TGATTTGGCCAATGGAAGGTAGTCATTGGCTAAATGTTAAGATAATTATAGATGAGCTCATTAAAAAGGA
  GCATAATGTGACTGTCCTAGTTGCCTCTGGTGCACTTTTCATCACACCAACCTCTAACCCATCTCTGACA
  TTTGAAATATATAGGGTGCCCTTTGGCAAAGAAAGAATAGAAGGAGTAATTAAGGACTTCGTTTTGACAT
  GGCTGGAAAATAGACCATCTCCTTCAACCATTTGGAGATTCTATCAGGAGATGGCCAAAGTAATCAAGGA
  CTTCCACATGGTGTCTCAGGAGATCTGTGATGGCGTTCTTAAAAACCAACAGCTGATGGCAAAGCTAAAG
  AAAAGCAAGTTTGAAGTCCTGGTGTCTGATCCAGTATTTCCTTGTGGCGATATAGTAGCTTTAAAACTTG
  GAATTCCATTTATGTACTCCTTGAGGTTTTCTCCAGCCTCAACAGTGGAAAAGCACTGTGGGAAGGTACC
  ATACCCTCCTTCCTATGTTCCTGCTGTTTTATCAGAACTCACCGACCAAATGTCTTTCACTGACAGAATA
  AGAAATTTCATCTCCTACCACCTACAGGACTACATGTTTGAAACTCTTTGGAAATCATGGGATTCATACT
  ATAGTAAAGCTTTAGGTGGACTCTTACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGGATCTTGGCTCACT
  GCAACCTCTGCTTCCCGGGTTCAAGCGATTCTCCCGCCTCAGCCTCCATTGTAGTTGGGATTACAGGCTG
  CCAGCAGGAAGACCCACTACGTTATGTGAGACTATGGGGAAAGCTGAAATTTGGTTAATCCGAACATATT
  GGGATTTTGAATTTCCTCGTCCATACTTACCTAATTTTGAGTTTGTTGGAGGATTGCACTGCAAACCTGC
  CAAACCTTTACCTAAGGTTTTATGGAGATACAAAGGAAAGAAACCAGCCACATTAGGAAACAATACTCAG
  CTCTTTGATTGGATACCCCAGAATGATCTTCTTGGACATCCCAAAACCAAAGCTTTTATCACTCATGGTG
  GAACTAATGGGATCTACGAAGCTATTTACCACGGAGTCCCTATGGTGGGAGTTCCCATGTTTGCTGATCA
  GCCTGATAACATTGCTCACATGAAGGCCAAAGGAGCAGCTGTGGAAGTGAACCTAAACACAATGACAAGT
  GTGGATTTGCTTAGCGCTTTGAGAACAGTCATTAATGAACCTTCTTATAAAGAGAATGCTATGAGGTTAT
  CAAGAATTCACCATGATCAACCTGTAAAGCCCCTGGATCGAGCAGTCTTCTGGATCGAGTTTGTCATGCG
  CCACAAAGGAGCCAAGCACCTTCGGGTTGCAGCCCATGACCTCACCTGGTTCCAGTACCACTCTTTGGAT
  GTAATTGGGTTCTTGCTGGTCTGTGTGACAACGGCTATATTTTTGGTCATACAATGTTGTTTGTTTTCCT
  GTCAAAAATTTGGTAAGATAGGAAAGAAGAAAAAAAGAGAATAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001252275
• ORF Size: 1584 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001252275.1, NP_001239204.1
• RefSeq Size: 2656
• RefSeq ORF: 1584
• Locus ID: 10941
• Protein Families: Transmembrane
• Protein Pathways: Androgen and estrogen metabolism, Ascorbate and aldarate metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pentose and glucuronate interconversions, Porphyrin and chlorophyll metabolism, Retinol metabolism, Starch and sucrose metabolism
• Gene Summary: The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. This gene shares exon structure with the UDP glucuronosyltransferase 2A2 family member, which encodes N-terminally distinct isoforms. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (3) lacks an alternate in-frame exon but instead contains a different in-frame exon in the central coding region, compared to variant 2. The encoded isoform (3) is shorter than isoform 2.