PITRM1 (NM_001242309) Human Untagged Clone

CAT#: SC331783

PITRM1 (untagged) - Homo sapiens pitrilysin metallopeptidase 1 (PITRM1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PITRM1
• Synonyms: MP1; PreP
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001242309, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCGCAATGTGGCGCTGCGGCGGGCGGCAGGGCCTGTGTGTGCTGAGGCGGCTGAGCGGCGGGTGACAT
  CTGTTCCCGAGCTGTTCCTGACTGCAGTGAAGCTCACCCATGATGACACAGGAGCCAGGTATTTACACCT
  GGCCAGAGAAGACACGAATAATCTGTTCAGCGTGCAGTTCCGTACTACTCCCATGGACAGTACTGGTGTT
  CCTCACATTCTTGAGCATACCGTCCTTTGTGGGTCTCAGAAATATCCGTGCAGAGACCCTTTCTTCAAAA
  TGTTGAACCGGTCCCTCTCCACGTTCATGAACGCCTTCACAGCTAGTGATTATACTCTGTATCCATTTTC
  CACACAAAATCCCAAGGACTTTCAGAATCTCCTCTCGGTGTATTTGGATGCCACCTTTTTCCCATGTTTA
  CGCGAGCTGGATTTCTGGCAGGAAGGATGGCGGCTGGAACATGAGAATCCGAGCGACCCCCAGACGCCCT
  TGGTCTTTAAAGGAGTCGTCTTTAATGAGATGAAGGGAGCGTTTACAGACAATGAGAGGATATTCTCCCA
  GCACCTTCAGAACAGACTTCTTCCTGACCACACGTACTCAGTGGTCTCCGGGGGTGACCCACTGTGCATC
  CCGGAGCTTACATGGGAGCAGCTTAAGCAGTTTCATGCCACTCACTATCACCCAAGCAATGCTAGGTTCT
  TCACGTACGGTAATTTTCCATTAGAACAGCATCTGAAACAAATTCACGAGGAAGCACTGAGCAAATTCCA
  GAAAATTGAACCAAGCACCGTGGTGCCAGCTCAGACACCCTGGGACAAGCCTAGGGAATTCCAGATAACA
  TGTGGCCCGGATTCATTTGCTACAGATCCCTCTAAACAAACAACCATCAGCGTTAGCTTCCTCTTACCGG
  ACATCACCGACACATTTGAAGCCTTCACATTAAGTCTTCTGTCTTCACTCTTGACTTCTGGGCCCAATTC
  TCCCTTTTACAAAGCCTTGATTGAATCTGGCCTTGGCACAGACTTTTCTCCTGATGTTGGATATAATGGC
  TACACGAGGGAGGCCTACTTTAGTGTCGGCCTCCAAGGGATTGCGGAGAAAGACATTGAGACCGTCAGAA
  GCCTCATAGACAGAACGATTGATGAAGTAGTTGAGAAAGGATTTGAAGATGATCGAATTGAGGCTTTACT
  TCATAAAATTGAAATACAGATGAAACATCAGTCTACCAGCTTTGGGCTGATGCTGACATCATACATAGCT
  TCTTGCTGGAACCATGATGGGGACCCTGTGGAGCTCTTGAAGTTGGGAAATCAGTTAGCTAAATTCAGAC
  AGTGCCTGCAGGAAAATCCAAAATTTTTGCAAGAAAAAGTAAAACAGTATTTTAAGAATAACCAGCATAA
  GCTGACTTTATCGATGAGGCCAGATGACAAGTATCACGAGAAGCAGGCACAGGTGGAAGCCACGAAGCTC
  AAGCAGAAGGTCGAGGCTCTGTCCCCCGGAGACAGGCAGCAGATCTACGAGAAAGGTCTAGAATTACGGA
  GTCAACAAAGCAAACCTCAAGATGCCTCTTGTCTGCCAGCGTTGAAAGTTTCCGATATTGAACCCACCAT
  ACCTGTCACAGAGTTGGACGTGGTCCTGACAGCTGGAGATATCCCTGTTCAGTACTGCGCCCAGCCCACC
  AATGGCATGGTGTATTTCCGGGCCTTCTCCAGCCTGAACACACTCCCCGAGGAGCTGAGGCCCTATGTGC
  CCCTCTTCTGCAGCGTCCTCACCAACCCGTGCTTTGAAGAAGAGGAGCACTTCAAGGTGCTGGTGAAGAT
  GACCGCCCAGGAGCTCGCCAATGGAATTCCTGACTCTGGGCACCTGTACGCATCCATCAGGGCAGGCCGG
  ACCCTCACGCCCGCAGGGGACCTGCAGGAGACCTTCAGCGGGATGGATCAGGTGCGGCTGATGAAGAGGA
  TTGCAGAAATGACAGATATCAAACCCATCCTGAGGAAGCTCCCGCGTATCAAGAAACACTTGTTAAATGG
  TGATAATATGAGGTGTTCAGTGAATGCGACTCCTCAGCAGATGCCTCAGACAGAAAAAGCGGTCGAAGAC
  TTCCTTAGAAGCATCGGTCGGAGTAAAAAGGAACGGAGGCCTGTGCGCCCACACACGGTCGAGAAACCTG
  TGCCCAGCAGCTCTGGTGGAGATGCCCACGTTCCCCATGGCTCCCAGGTCATTAGGAAGCTGGTCATGGA
  ACCCACCTTCAAGCCCTGGCAGATGAAGACTCACTTCCTGATGCCCTTCCCGGTGAATTACGTGGGTGAA
  TGCATCCGAACTGTCCCCTACACGGACCCAGATCATGCCAGTCTTAAAATCCTTGCACGTTTGATGACTG
  CCAAATTCTTGCATACAGAAATTCGAGAAAAAGGCGGTGCTTATGGTGGAGGCGCAAAACTCAGCCACAA
  TGGGATTTTCACCCTTTACTCTTACAGGGACCCAAATACAATAGAGACGCTCCAGTCTTTTGGGAAGGCT
  GTCGACTGGGCTAAGTCTGGAAAATTCACACAGCAAGACATCGACGAAGCCAAACTTTCTGTCTTCTCAA
  CCGTAGATGCTCCTGTCGCTCCTTCAGACAAAGGAATGGACCACTTCTTGTACGGCCTCTCGGATGAGAT
  GAAGCAGGCCCACAGAGAGCAGCTCTTTGCTGTCAGCCACGACAAGCTCCTGGCCGTGAGCGATAGATAC
  CTCGGCACTGGGAAGAGCACACACGGCCTGGCCATCCTCGGACCCGAGAACCCGAAAATTGCCAAGGACC
  CATCCTGGATCATCCAATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001242309
• ORF Size: 2820 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001242309.1, NP_001229238.1
• RefSeq Size: 3198
• RefSeq ORF: 2820
• Locus ID: 10531
• Protein Families: Druggable Genome, Protease
• Gene Summary: The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease. [provided by RefSeq, Dec 2016]
  Transcript Variant: This variant (3) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at an alternate AUG and results an isoform (3) with a distinct N-terminus, compared to isoform 1. The encoded protein likely does not localize to the mitochondrion. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.