RIN2 (NM_001242581) Human Untagged Clone

CAT#: SC331829

RIN2 (untagged) - Homo sapiens Ras and Rab interactor 2 (RIN2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RIN2
• Synonyms: MACS; RASSF4
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001242581, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTGGACTCATTTTCTCAAGAATCCACTTTACCCTTCAGGGAAGCCAGGAAAAGAACAAGCTTCCAAC
  CGGTACAAGTCTGGAGGAATTTCACAGCCTCTCAAACTACGGAGTCCCCGGCGTGCAGTGGAGCCTCGCT
  GGGGGAAATGACAGCTTGGACCATGGGCGCCCGCGGTCTGGACAAGCGAGGAAGTTTCTTTAAGCTCATT
  GACACAATTGCCTCGGAGATCGGAGAACTGAAACAGGAGATGGTGCGGACAGATGTCAACCTGGAAAATG
  GCCTGGAACCCGCTGAAACCCACAGCATGGTAAGACACAAGGATGGTGGCTATTCCGAGGAAGAGGACGT
  GAAGACCTGTGCCCGGGACTCAGGCTATGACAGCCTCTCCAACAGGCTCAGCATCTTGGACCGGCTCCTC
  CACACCCACCCCATATGGCTGCAGCTGAGTCTGAGTGAGGAGGAGGCAGCAGAGGTCCTGCAGGCCCAGC
  CTCCGGGGATCTTCCTGGTTCATAAATCTACCAAGATGCAGAAGAAAGTCCTCTCCCTCCGCCTGCCCTG
  TGAATTTGGGGCCCCACTCAAGGAATTTGCCATAAAGGAAAGCACATACACCTTTTCCCTGGAAGGCTCA
  GGAATCAGTTTCGCAGATTTATTCCGGCTCATTGCTTTCTACTGCATCAGCAGGGATGTTCTACCATTTA
  CCTTGAAGTTGCCTTATGCCATTTCAACAGCCAAGTCGGAGGCTCAGCTTGAAGAACTGGCCCAGATGGG
  ACTAAATTTCTGGAGCTCCCCAGCTGACAGCAAACCCCCGAACCTTCCACCTCCCCATAGGCCTCTTTCC
  TCCGACGGTGTCTGTCCTGCCTCCCTGCGTCAGCTCTGCCTTATAAATGGAGTGCATTCTATCAAAACCA
  GGACGCCTTCAGAGCTGGAGTGCAGCCAGACCAACGGGGCCCTGTGCTTTATTAATCCCCTTTTCTTGAA
  AGTGCACAGCCAGGACCTCAGTGGAGGCCTGAAACGGCCGAGCACAAGGACTCCCAACGCGAATGGCACG
  GAGCGGACTCGGTCCCCCCCACCCAGGCCCCCGCCACCCGCTATTAATAGTCTCCACACAAGCCCTCGGC
  TGGCCAGGACTGAAACCCAGACGAGCATGCCAGAAACAGTCAACCATAACAAACATGGGAACGTAGCTCT
  GCCTGGAACGAAACCAACTCCCATCCCTCCACCCCGGCTGAAGAAGCAGGCTTCTTTTCTGGAAGCAGAG
  GGCGGTGCAAAGACCTTGAGCGGCGGCCGGCCGGGCGCAGGCCCGGAGCTGGAGCTGGGCACAGCTGGCA
  GCCCAGGTGGGGCCCCGCCTGAGGCCGCCCCGGGGGATTGCACAAGGGCCCCGCCGCCCAGCTCTGAATC
  ACGGCCCCCGTGCCATGGAGGCCGGCAGCGGCTGAGCGACATGAGCATTTCTACTTCCTCCTCCGACTCG
  CTGGAGTTCGACCGGAGCATGCCTCTGTTTGGCTACGAGGCGGACACCAACAGCAGCCTGGAGGACTACG
  AGGGGGAAAGTGACCAAGAGACCATGGCGCCCCCCATCAAGTCCAAAAAGAAAAGGAGCAGCTCCTTCGT
  GCTGCCCAAGCTCGTCAAGTCCCAGCTGCAGAAGGTGAGCGGGGTGTTCAGCTCCTTCATGACCCCGGAG
  AAGCGGATGGTCCGCAGGATCGCCGAGCTTTCCCGGGACAAATGCACCTACTTCGGGTGCTTAGTGCAGG
  ACTACGTGAGCTTCCTGCAGGAGAACAAGGAGTGCCACGTGTCCAGCACCGACATGCTGCAGACCATCCG
  GCAGTTCATGACCCAGGTCAAGAACTATTTGTCTCAGAGCTCGGAGCTGGACCCCCCCATCGAGTCGCTG
  ATCCCTGAAGACCAAATAGATGTGGTGCTGGAAAAAGCCATGCACAAGTGCATCTTGAAGCCCCTCAAGG
  GGCACGTGGAGGCCATGCTGAAGGACTTTCACATGGCCGATGGCTCATGGAAGCAACTCAAGGAGAACCT
  GCAGCTTGTGCGGCAGAGGAATCCGCAGGAGCTGGGGGTCTTCGCCCCGACCCCTGATTTTGTGGATGTG
  GAGAAAATCAAAGTCAAGTTCATGACCATGCAGAAGATGTATTCGCCGGAAAAGAAGGTCATGCTGCTGC
  TGCGGGTCTGCAAGCTCATTTACACGGTCATGGAGAACAACTCAGGGAGGATGTATGGCGCTGATGACTT
  CTTGCCAGTCCTGACCTATGTCATAGCCCAGTGTGACATGCTTGAATTGGACACTGAAATCGAGTACATG
  ATGGAGCTCCTAGACCCATCGCTGTTACATGGAGAAGGAGGCTATTACTTGACAAGCGCATATGGAGCAC
  TTTCTCTGATAAAGAATTTCCAAGAAGAACAAGCAGCGCGACTGCTCAGCTCAGAAACCAGAGACACCCT
  GAGGCAGTGGCACAAACGGAGAACCACCAACCGGACCATCCCCTCTGTGGACGACTTCCAGAATTACCTC
  CGAGTTGCATTTCAGGAGGTCAACAGTGGTTGCACAGGAAAGACCCTCCTTGTGAGACCTTACATCACCA
  CTGAGGATGTGTGTCAGATCTGCGCTGAGAAGTTCAAGGTGGGGGACCCTGAGGAGTACAGCCTCTTTCT
  CTTCGTTGACGAGACATGGCAGCAGCTGGCAGAGGACACTTACCCTCAAAAAATCAAGGCGGAGCTGCAC
  AGCCGACCACAGCCCCACATCTTCCACTTTGTCTACAAACGCATCAAGAACGATCCTTATGGCATCATTT
  TCCAGAACGGGGAAGAAGACCTCACCACCTCCTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001242581
• ORF Size: 2835 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001242581.1, NP_001229510.1
• RefSeq Size: 4525
• RefSeq ORF: 2835
• Locus ID: 54453
• Gene Summary: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).