Zonula occludens protein 3 (TJP3) (NM_001267560) Human Untagged Clone

CAT#: SC332852

TJP3 (untagged) - Homo sapiens tight junction protein 3 (TJP3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TJP3
• Synonyms: ZO-3; ZO3
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001267560, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGGAGCTGACCATCTGGGAACAGCACACGGCCACACTGTCCAAGGACCCCCGCCGGGGCTTTGGCA
  TTGCGATCTCTGGAGGCCGAGACCGGCCCGGTGGATCCATGGTTGTATCTGACGTGGTACCTGGAGGGCC
  GGCGGAGGGCAGGCTACAGACAGGCGACCACATCGTCATGGTGAACGGGGTTTCCATGGAGAATGCCACC
  TCCGCGTTTGCCATTCAGATACTCAAGACCTGCACCAAGATGGCCAACATCACAGTGAAACGTCCCCGGA
  GGATCCACCTGCCCGCCACCAAAGCCAGCCCCTCCAGCCCAGGGCGCCAGGACTCGGATGAAGACGATGG
  GCCCCAGCGGGTGGAGGAGGTGGACCAGGGCCGGGGCTATGACGGCGACTCATCCAGTGGCTCCGGCCGC
  TCCTGGGACGAGCGCTCCCGCCGGCCGAGGCCTGGTCGCCGGGGCCGGGCCGGCAGCCATGGGCGTAGGA
  GCCCAGGTGGTGGCTCTGAGGCCAACGGGCTGGCCCTGGTGTCCGGCTTTAAGCGGCTGCCACGGCAGGA
  CGTGCAGATGAAGCCTGTGAAGTCAGTGCTGGTGAAGAGGAGAGACAGCGAAGAGTTTGGCGTCAAGCTG
  GGCAGTCAGATCTTCATCAAGCACATTACAGATTCGGGCCTGGCTGCCCGGCACCGTGGGCTGCAGGAAG
  GAGATCTCATTCTACAGATCAACGGGGTGTCTAGCCAGAACCTGTCACTGAACGACACCCGGCGACTGAT
  TGAGAAGTCAGAAGGGAAGCTAAGCCTGCTGGTGCTGAGAGATCGTGGGCAGTTCCTGGTGAACATTCCG
  CCTGCTGTCAGTGACAGCGACAGCTCGCCATTGGAGGACATCTCGGACCTCGCCTCGGAGCTATCGCAGG
  CACCACCATCCCACATCCCACCACCACCCCGGCATGCTCAGCGGAGCCCCGAGGCCAGCCAGACCGACTC
  TCCCGTGGAGAGTCCCCGGCTTCGGCGGGAAAGTTCAGTAGATTCCAGAACCATCTCGGAACCAGATGAG
  CAACGGTCAGAGTTGCCCAGGGAAAGCAGCTATGACATCTACAGAGTGCCCAGCAGTCAGAGCATGGAGG
  ATCGTGGGTACAGCCCCGACACGCGTGTGGTCCGCTTCCTCAAGGGCAAGAGCATCGGGCTGCGGCTGGC
  AGGGGGCAATGACGTGGGCATCTTCGTGTCCGGGGTGCAGGCGGGCAGCCCGGCCGACGGGCAGGGCATC
  CAGGAGGGAGATCAGATTCTGCAGGTGAATGACGTGCCATTCCAGAACCTGACACGGGAGGAGGCAGTGC
  AGTTCCTGCTGGGGCTGCCACCAGGCGAGGAGATGGAGCTGGTGACGCAGAGGAAGCAGGACATTTTCTG
  GAAAATGGTGCAGTCCCGCGTGGGTGACTCCTTCTACATCCGCACTCACTTTGAGCTGGAGCCCAGTCCA
  CCGTCTGGCCTGGGCTTCACCCGTGGCGACGTCTTCCACGTGCTGGACACGCTGCACCCCGGCCCCGGGC
  AGAGCCACGCACGAGGAGGCCACTGGCTGGCGGTGCGCATGGGTCGTGACCTGCGGGAGCAAGAGCGGGG
  CATCATTCCCAACCAGAGCAGGGCGGAGCAGCTGGCCAGCCTGGAAGCTGCCCAGAGGGCCGTGGGAGTC
  GGGCCCGGCTCCTCCGCGGGCTCCAATGCTCGGGCCGAGTTCTGGCGGCTGCGGGGTCTTCGTCGAGGAG
  CCAAGAAGACCACTCAGCGGAGCCGTGAGGACCTCTCAGCTCTGACCCGACAGGGCCGCTACCCGCCCTA
  CGAACGAGTGGTGTTGCGAGAAGCCAGTTTCAAGCGCCCGGTAGTGATCCTGGGACCCGTGGCCGACATT
  GCTATGCAGAAGTTGACTGCTGAGATGCCTGACCAGTTTGAAATCGCAGAGACTGTGTCCAGGACCGACA
  GCCCCTCCAAGATCATCAAACTAGACACCGTGCGGGTGATTGCAGAAAAAGACAAGCATGCGCTCCTGGA
  TGTGACCCCCTCCGCCATCGAGCGCCTCAACTATGTGCAGTACTACCCCATTGTGGTCTTCTTCATCCCC
  GAGAGCCGGCCGGCCCTCAAGGCACTGCGCCAGTGGCTGGCGCCTGCCTCCCGCCGCAGCACCCGTCGCC
  TCTACGCACAAGCCCAGAAGCTGCGAAAACACAGCAGCCACCTCTTCACAGCCACCATCCCTCTGAATGG
  CACGAGTGACACCTGGTACCAGGAGCTCAAGGCCATCATTCGAGAGCAGCAGACGCGGCCCATCTGGACG
  GCGGAAGATCAGCTGGATGGCTCCTTGGAGGACAACCTAGACCTCCCTCACCACGGCCTGGCCGACAGCT
  CCGCTGACCTCAGCTGCGACAGCCGCGTTAACAGCGACTACGAGACGGACGGCGAGGGCGGCGCGTACAC
  GGATGGCGAGGGCTACACAGACGGCGAGGGGGGGCCCTACACGGATGTGGATGATGAGCCCCCGGCTCCA
  GCCCTGGCCCGGTCCTCGGAGCCCGTGCAGGCAGATGAGTCCCAGAGCCCGAGGGATCGTGGGAGAATCT
  CGGCTCATCAGGGGGCCCAGGTGGACAGCCGCCACCCCCAGGGACAGTGGCGACAGGACAGCATGCGAAC
  CTATGAACGGGAAGCCCTGAAGAAAAAGTTTATGCGAGTACATGATGCGGAGTCCTCCGATGAAGACGGC
  TATGACTGGGGTCCGGCCACTGACCTGTGA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001267560
• ORF Size: 2760 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001267560.1, NP_001254489.1
• RefSeq Size: 3140
• RefSeq ORF: 2760
• Locus ID: 27134
• Protein Pathways: Tight junction
• Gene Summary: The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012]
  Transcript Variant: This variant (1) represents the longer transcript and encodes isoform 1.