ARFGAP1 (NM_001281482) Human Untagged Clone

CAT#: SC335899

ARFGAP1 (untagged) - Human ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARFGAP1
• Synonyms: ARF1GAP; HRIHFB2281
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001281482, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCAGCCCAAGAACCAGGAAGGTTCTTAAAGAAGTCAGGGTGCAGGATGAGAACAACGTTTGTTTTG
  AGTGTGGCGCGTTCAATCCTCAGTGGGTCAGTGTGACCTACGGCATCTGGATCTGCCTGGAGTGCTCGGG
  GAGACACCGCGGGCTTGGGGTTCACCTCAGCTTTGTGCGCTCTGTTACTATGGACAAGTGGAAGGACATT
  GAGCTTGAGAAGATGAAAGCTGGTGGGAATGCTAAGTTCCGAGAGTTCCTGGAGTCTCAGGAGGATTACG
  ATCCTTGCTGGTCCTTGCAGGAGAAGTACAACAGCAGAGCCGCGGCCCTCTTTAGGGATAAGGTGGTCGC
  TCTGGCCGAAGGCAGAGAGTGGTCTCTGGAGTCATCACCTGCCCAGAACTGGACCCCACCTCAGCCCAGG
  ACGCTGCCGTCCATGGTGCACCGAGTCTCTGGCCAGCCGCAGAGTGTGACCGCCTCCTCGGACAAGGCTT
  TTGAAGACTGGCTGAATGATGACCTCGGCTCCTATCAAGGGGCCCAGGGGAATCGCTACGTGGGGTTTGG
  GAACACGCCACCGCCTCAGAAGAAAGAAGATGACTTCCTCAACAACGCCATGTCCTCCCTGTACTCGGGC
  TGGAGCAGCTTCACCACTGGAGCCAGCCGGTTTGCCTCGGCAGCCAAGGAGGGCGCTACAAAGTTTGGAT
  CCCAAGCGAGTCAGAAGGCGTCCGAGCTGGGCCACAGCCTGAACGAGAACGTCCTCAAGCCTGCGCAGGA
  GAAGGTGAAGGAGGGAAAGATTTTTGATGATGTCTCCAGTGGGGTCTCTCAGTTGGCGTCCAAGTGCCAG
  CGCCGTCTTTGCTGCCATCAGTCCCACTGCTCTGCGGGCCATTTGGGGCGTGCATTTTGTCCTGTTTCCT
  GGCATGAGGCGCTCTGCGGACAGACGGGGAGGGAAGAGCAGGCCTCGCTCCTCCCCCCCAAGCATGTGGT
  GGGAGCTCTTGAGGTCTGTGCACGAGGCTGTCCTCGCTGCCATGTCCCGCACACACCTGGCACCGCTGCA
  GAGTGGCCGGGGCGTCTGTGTCTGTCCAGGGAGTCGGTAGTAAGGGATGGCGGGACGTCACCACCTTTTT
  TTCGGGGAAAGCAGAGGGCCCCTTGGACAGCCCCTCGGAGGGCCACAGTTATCAGAACAGCGGTCTGGAC
  CACTTCCAAAACAGCAACATAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001281482
• ORF Size: 1212 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001281482.1, NP_001268411.1
• RefSeq Size: 3524
• RefSeq ORF: 1212
• Locus ID: 55738
• Protein Pathways: Endocytosis
• Gene Summary: The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (3) has multiple differences in the coding region, which results in a translational frameshift, compared to variant 2. The encoded isoform (c) has a shorter and distinct C-terminus, compared to isoform b.