CTP synthase (CTPS1) (NM_001301237) Human Untagged Clone

CAT#: SC336112

CTPS1 (untagged) - Human CTP synthase 1 (CTPS1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CTPS1
• Synonyms: CTPS; GATD5; IMD24
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001301237, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCCTTTATTGAGGCCTTCCGTCAGTTCCAATTCAAGGTCAAAAGAGAGAACTTTTGTAACATCCACG
  TCAGTCTAGTTCCCCAGCCAAGTTCAACAGGGGAACAGAAGACTAAACCTACCCAGAATAGTGTTCGGGA
  ACTTAGAGGACTTGGGCTTTCCCCAGATCTGGTTGTATGCAGGTGCTCAAATCCACTTGACACATCAGTG
  AAGGAGAAAATATCAATGTTCTGCCATGTTGAGCCTGAACAAGTGATCTGTGTCCACGATGTCTCATCCA
  TCTACCGAGTCCCCTTGTTGTTAGAGGAGCAAGGGGTTGTAGATTATTTTCTTCGAAGACTTGACCTTCC
  TATTGAGAGGCAGCCAAGAAAAATGCTGATGAAATGGAAAGAGATGGCTGACAGATATGATCGCTTGCTG
  GAGACCTGCTCTATTGCCCTTGTGGGCAAATACACGAAGTTCTCAGACTCCTATGCCTCTGTCATTAAGG
  CTCTGGAGCATTCTGCACTGGCCATCAACCACAAATTGGAAATCAAGTACATAGATTCTGCGGACTTGGA
  GCCCATCACCTCGCAAGAAGAGCCCGTGCGCTACCACGAAGCTTGGCAGAAGCTCTGTAGTGCTCATGGA
  GTGCTGGTTCCAGGAGGATTTGGTGTTCGAGGAACAGAAGGAAAAATCCAAGCAATTGCCTGGGCTCGGA
  ATCAGAAAAAGCCTTTTTTGGGCGTGTGCTTAGGGATGCAGTTGGCAGTGGTTGAATTCTCAAGAAACGT
  GCTGGGATGGCAAGATGCCAATTCTACAGAGTTTGACCCTACGACCAGTCATCCCGTGGTCGTAGACATG
  CCAGAACACAACCCAGGGCAGATGGGCGGAACCATGAGGCTGGGCAAGAGGAGAACCCTGTTCCAGACCA
  AGAACTCAGTCATGAGGAAACTCTATGGAGACGCAGACTACTTGGAAGAGAGGCACCGCCACCGATTTGA
  GGTGAATCCAGTCTGGAAAAAGTGTTTGGAAGAACAAGGCTTGAAGTTTGTTGGCCAAGATGTTGAAGGA
  GAGAGAATGGAAATTGTGGAGTTAGAAGATCATCCCTTTTTTGTTGGGGTTCAGTACCACCCTGAGTTCC
  TGTCCAGGCCTATCAAGCCCTCCCCACCATACTTTGGCCTCCTCCTGGCCTCTGTGGGGCGGCTCTCACA
  TTACCTCCAGAAAGGCTGCAGGCTCTCACCCAGGGACACCTATAGTGACAGGAGTGGAAGCAGCTCCCCT
  GACTCTGAAATCACCGAACTGAAGTTTCCATCAATAAATCATGACTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001301237
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001301237.1, NP_001288166.1
• RefSeq Size: 2412 bp
• RefSeq ORF: 1308 bp
• Locus ID: 1503
• Cytogenetics: 1p34.2
• Protein Pathways: Metabolic pathways, Pyrimidine metabolism
• Gene Summary: 'This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]'
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks multiple 5' coding exons, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus than isoform a.