SPATA18 (NM_001297608) Human Untagged Clone

CAT#: SC336507

SPATA18 (untagged) - Human spermatogenesis associated 18 (SPATA18), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPATA18
• Synonyms: Mieap; SPETEX1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001297608, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGAAAACCTGAAAAGACTGGTCTCAAACGAAACTTTACGAACGTTGCAGGAAAAGCTAGACTTCT
  GGCTGAAGGAGTACAACACAAACACGTGTGATCAAAATCTAAACCATTGCCTTGAACTCATTGAGCAAGT
  TGCCAAGGTGCAGGGACAACTCTTTGGGATCCTCACAGCAGCAGCCCAAGAAGGAGGACGTAATGATGGT
  GTGGAAACAATCAAGTCACGCCTTTTGCCTTGGCTGGAGGCTTCCTTTACTGCTGCTTCCCTGGGAAAAT
  CTGTTGACAGCAAGGTCCCCTCTCTGCAGGACACGTTTGATAGGGAGAGACATAAAGATCCCAGTCCTCG
  GGATCGGGATATGCAACAGTTAGACTCTAATTTGAACTCAACCCGGAGTCAATGCAACCAGGTTCAAGAC
  GAGCTTAAATCTCTTCAAGCTCAGGAGGATGCCCGCCACAGAAACACAGATCAGAGGAGCTCAGAGAATA
  GGCGGTCAGAGCCTTGGAGCTTGGAGGAGCGGAAGCGTGAGCAGTGGAACTCACTCAAGCAGAATGCAGA
  CCAGCAGGACACAGAAGCCATGTCCGATTATAAGAAACAGCTCCGAAACCTGAAGGAGGAGATAGCTGTT
  CTGTCTGCTGAGAAAAGTGCACTCCAAGGAAGGTCCTCCAGGAGCCGGTCTCCCAGCCCTGCCCCTCGCA
  GCCGTAGCTGCAGCCGCAGCAGATCTGCCAGCCCCTCCACCGCTGTCAAGGTCAGGAGACCGTCCCCAAA
  CCGCTCCAAGCTGTCCAATGTGGCGCGCAAGGCTGCCCTCTTGTCCCGGTTCAGCGATTCCTATTCCCAG
  GCCCGCCTGGACGCGCAGTGCCTGCTGCGGCGCTGCATCGACAAGGCTGAGACCGTTCAGCGGATCATCT
  ACATCGCCACAGTGGAGGCATTCCATGTAGCAAAAATGGCATTCAGACACTTCAAGATCCATGTGAGAAA
  ATCGTTGACACCATCTTATGTGGGGTCGAATGACTTTGAGAATGCTGTCTTGGATTATGTCATTTGTCAT
  CTTGATCTATATGATTCTCAAAGCAGTGTCAATGATGTGATCCGAGCCATGAATGTCAATCCCAAGATTT
  CATTCCCTCCTGTCGTTGACTTTTGCCTTCTCAGTGACTTCATCCAGGAGATATGTTGCATTGCCTTTGC
  AATGCAGGCCTTAGAACCACCCCTAGATATTGCATATGGAGCAGATGGAGAAGTTTTTAATGATTGCAAA
  TACCGCCGCAGCTACGACTCGGATTTCACTGCTCCCTTAGTCCTCTATCACGTGTGGCCTGCTCTCATGG
  AGAATGACTGTGTCATTATGAAGGGAGAAGCTGTCACCAGGAGAGGGGCTTTTTGGAATTCGGTGCGATC
  TGTAAGTCGTTGTCGAAGCAGGAGTTTAAGTCCCATTTGCCCCCGTAGCCAAATTGGTTTAAACACGATG
  TCTCGAAGTCGGAGTCCTTCTCCAATAAGATGTGGATTGCCAAGATTTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001297608
• ORF Size: 1521 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001297608.1, NP_001284537.1
• RefSeq Size: 4329
• RefSeq ORF: 1521
• Locus ID: 132671
• Gene Summary: This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]