CCBL1 (KYAT1) (NM_001287390) Human Untagged Clone

CAT#: SC336574

CCBL1 (untagged) - Human cysteine conjugate-beta lyase, cytoplasmic (CCBL1), transcript variant 4


  "NM_001287390" in other vectors (1)

Reconstitution Protocol

USD 530.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol KYAT1
Synonyms CCBL1; GTK; KAT1; KATI
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>NCBI ORF sequence for NM_001287390, the custom clone sequence may differ by one or more nucleotides


ATGTTCAGGACTGCAGCAGCCATCTCTGTGCACCTGGTGGGGCCCCTTCAGGGAAGGAAGGCTGGAGCCC
CACTCACTTGGTTCTTGCACCAGACTCAGGTGGCTGAGAAGAATGTTGGATCCCCAGCTCCACGGCCCAC
CAGCCATCTGGGACTGGCAAACCCACAGGAACGGAAGGTTCCTCAGGGACCACAAAGCCCATGTGAGGTC
CCTGCTGCTGAAGGGATTCTGAGGACAGGAGGAGCCAAATTACCTATCCAGGGTCACCCAGCCAAGCTCG
CCATGGCCAAACAGCTGCAGGCCCGAAGGCTAGACGGGATCGACTACAACCCCTGGGTGGAGTTTGTGAA
ACTGGCCAGTGAGCATGACGTCGTGAACTTGGGCCAGGGCTTCCCGGATTTCCCACCACCAGACTTTGCC
GTGGAAGCCTTTCAGCACGCTGTCAGTGGAGACTTCATGCTTAACCAGTACACCAAGACATTTGGTTACC
CACCACTGACGAAGATCCTGGCAAGTTTCTTTGGGGAGCTGCTGGGTCAGGAGATAGACCCGCTCAGGAA
TGTGCTGGTGACTGTTGGTGGCTATGGGGCCCTGTTCACAGCCTTCCAGGCCCTGGTGGACGAAGGAGAC
GAGGTCATCATCATCGAACCCTTTTTTGACTGCTACGAGCCCATGACAATGATGGCAGGGGGTCGTCCTG
TGTTTGTGTCCCTGAAGCCGGGTCCCATCCAGAATGGAGAACTGGGTTCCAGCAGCAACTGGCAGCTGGA
CCCCATGGAGCTGGCCGGCAAATTCACATCACGCACCAAAGCCCTGGTCCTCAACACCCCCAACAACCCC
CTGGGCAAGGTGTTCTCCAGGGAAGAGCTGGAGCTGGTGGCCAGCCTTTGCCAGCAGCATGACGTGGTGT
GTATCACTGATGAAGTCTACCAGTGGATGGTCTACGACGGGCACCAGCACATCAGCATTGCCAGCCTCCC
TGGCATGTGGGAACGGACCCTGACCATCGGCAGCGCCGGCAAGACCTTCAGCGCCACTGGCTGGAAGGTG
GGCTGGGTCCTGGGTCCAGATCACATCATGAAGCACCTGCGGACCGTGCACCAGAACTCCGTCTTCCACT
GCCCCACGCAGAGCCAGGCTGCAGTAGCCGAGAGCTTTGAACGGGAGCAGCTGCTCTTCCGCCAACCCAG
CAGCTACTTTGTGCAGTTCCCGCAGGCCATGCAGCGCTGCCGTGACCACATGATACGTAGCCTACAGTCA
GTGGGCCTGAAGCCCATCATCCCTCAGGGCAGCTACTTCCTCATCACAGACATCTCAGACTTCAAGAGGA
AGATGCCTGACTTGCCTGGAGCTGTGGATGAGCCCTATGACAGACGCTTCGTCAAGTGGATGATCAAGAA
CAAGGGCTTGGTGGCCATCCCTGTCTCCATCTTCTATAGTGTGCCACATCAGAAGCACTTTGACCACTAT
ATCCGCTTCTGTTTTGTGAAGGATGAAGCCACGCTCCAGGCCATGGACGAGAAGCTGCGGAAGTGGAAGG
TGGAACTCTAG


Restriction Sites SgfI-MluI     
ACCN NM_001287390
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001287390.1, NP_001274319.1
RefSeq Size 2487 bp
RefSeq ORF 1551 bp
Locus ID 883
Cytogenetics 9q34.11
Gene Summary 'This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (4) differs in the 5' UTR and CDS, and uses an alternate upstream translation start, compared to variant 1. The resulting protein (isoform c) has a longer N-terminus, compared to isoform a. Variants 4 and 12 both encode the same isoform (c). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.