PIF1 (NM_001286499) Human Untagged Clone

CAT#: SC336892

PIF1 (untagged) - Human PIF1 5'-to-3' DNA helicase (PIF1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PIF1
• Synonyms: C15orf20; PIF
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001286499, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTGCGGCTGCAAGCGCCAGGGCCCGCGGGGCGGCCGCGCTGCTTTCCTCTGCGCGCCGCGCGCCTCT
  TCACGCGTTTCGCCGAGGCCGGGCGCAGCACCCTGCGGCTCCCCGCCCACGACACCCCCGGGGCCGGCGC
  AGTGCAGCTGCTGCTCTCGGACTGCCCCCCAGACCGCCTGCGCCGCTTCCTGCGCACATTGCGCCTCAAG
  CTGGCTGCGGCCCCGGGTCCCGGGCCGGCCTCCGCCCGAGCGCAGCTGCTGGGCCCGCGGCCCCGCGACT
  TCGTCACCATCAGCCCTGTGCAGCCCGAGGAGCGGCGGCTCAGGGCGGCCACCCGGGTTCCGGACACTAC
  GCTGGTGAAGCGGCCTGTGGAGCCCCAGGCTGGGGCCGAGCCTAGCACAGAAGCCCCAAGGTGGCCCCTG
  CCTGTGAAGAGGCTGAGCTTGCCCTCCACCAAGCCACAGCTTTCTGAGGAACAGGCTGCTGTGCTGAGGG
  CCGTCCTGAAAGGCCAGAGCATCTTCTTCACTGGGAGTGCAGGAACAGGGAAGTCATATCTGCTAAAGCG
  AATCCTGGGCTCACTGCCCCCCACAGGCACTGTGGCCACTGCCAGCACTGGGGTGGCAGCCTGCCACATC
  GGGGGCACCACCCTCCATGCCTTTGCAGGCATCGGCTCAGGCCAGGCTCCTCTAGCCCAGTGTGTGGCCC
  TGGCCCAAAGGCCAGGCGTGCGGCAGGGCTGGCTGAACTGCCAGCGGTTGGTCATTGACGAGATCTCAAT
  GGTGGAGGCAGACCTGTTTGACAAACTGGAGGCCGTGGCCAGAGCTGTCCGGCAGCAGAACAAGCCATTC
  GGAGGGATCCAGCTCATCATCTGTGGGGACTTTCTGCAGCTGCCACCTGTGACCAAGGGCTCCCAGCCCC
  CACGGTTCTGCTTCCAGTCCAAGAGCTGGAAGAGGTGTGTGCCAGTGACCCTGGAGCTGACCAAGGTGTG
  GAGGCAGGCAGACCAGACCTTCATCTCTCTACTGCAGGCCGTGAGGCTAGGCAGGTGTTCAGATGAGGTG
  ACCCGCCAGCTCCAGGCCACAGCTTCCCACAAGGTGGGGCGAGATGGGATTGTGGCCACGAGGCTCTGCA
  CCCACCAGGATGATGTGGCCCTCACCAACGAGAGGCGGCTTCAGGAGCTGCCAGGTAAGGTACACAGATT
  TGAGGCTATGGACAGCAACCCTGAGCTGGCCAGTACCCTGGATGCCCAGTGTCCTGTTAGCCAGCTCCTT
  CAACTAAAGCTGGGGGCCCAGGTGATGCTGGTGAAAAACTTATCGGTGTCTCGGGGCCTGGTGAATGGTG
  CCCGAGGGGTGGTAGTTGGGTTCGAGGCAGAAGGGAGAGGGCTACCCCAGGTGCGGTTCCTGTGTGGAGT
  CACTGAGGTCATCCACGCTGACCGCTGGACGGTGCAGGCCACCGGGGGCCAGCTCCTCAGTCGGCAGCAG
  CTGCCCCTCCAGCTGGCCTGGGCGATGTCCATCCACAAGAGCCAAGGCATGACCCTGGATTGTGTGGAGA
  TTTCTCTGGGCCGTGTGTTTGCCAGTGGCCAGGCCTATGTGGCCCTTTCTCGGGCCCGCAGCCTGCAGGG
  CCTACGTGTGCTGGACTTTGACCCCATGGCGGTTCGCTGTGACCCCCGTGTGCTGCACTTCTATGCCACC
  CTGCGGCGGGGCAGGAGCCTCAGTCTGGAGTCCCCAGATGATGATGAGGCAGCCTCAGACCAGGAGAACA
  TGGACCCAATCCTCTGA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001286499
• ORF Size: 1767 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001286499.1, NP_001273428.1
• RefSeq Size: 2718
• RefSeq ORF: 1767
• Locus ID: 80119
• Gene Summary: This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus. [provided by RefSeq, Nov 2013]
  Transcript Variant: This variant (1) represents the longest transcript. This variant can initiate translation from both an upstream and a downstream AUG start codon. The isoform represented in this variant (c, also known as alpha-54) initiates translation from a downstream AUG. This isoform localizes to the mitochondria (PMID: 23275553).