RTEL1 (NM_001283009) Human Untagged Clone

CAT#: SC337994

RTEL1 (untagged) - Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RTEL1
• Synonyms: C20orf41; DKCA4; DKCB5; NHL; PFBMFT3; RTEL
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001283009, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCCAAGATAGTCCTGAATGGTGTGACCGTAGACTTCCCTTTCCAGCCCTACAAATGCCAACAGGAGT
  ACATGACCAAGGTCCTGGAATGTCTGCAGCAGAAGGTGAATGGCATCCTGGAGAGCCCTACGGGTACAGG
  GAAGACGCTGTGCCTGCTGTGCACCACGCTGGCCTGGCGAGAACACCTCCGAGACGGCATCTCTGCCCGC
  AAGATTGCCGAGAGGGCGCAAGGAGAGCTTTTCCCGGATCGGGCCTTGTCATCCTGGGGCAACGCTGCTG
  CTGCTGCTGGAGACCCCATAGCTTGCTACACGGACATCCCAAAGATTATTTACGCCTCCAGGACCCACTC
  GCAACTCACACAGGTCATCAACGAGCTTCGGAACACCTCCTACCGGCCTAAGGTGTGTGTGCTGGGCTCC
  CGGGAGCAGCTGTGCATCCATCCTGAGGTGAAGAAACAAGAGAGTAACCATCTACAGATCCACTTGTGCC
  GTAAGAAGGTGGCAAGTCGCTCCTGTCATTTCTACAACAACGTAGAAGAAAAAAGCCTGGAGCAGGAGCT
  GGCCAGCCCCATCCTGGACATTGAGGACTTGGTCAAGAGCGGAAGCAAGCACAGGGTGTGCCCTTACTAC
  CTGTCCCGGAACCTGAAGCAGCAAGCCGACATCATATTCATGCCGTACAATTACTTGTTGGATGCCAAGA
  GCCGCAGAGCACACAACATTGACCTGAAGGGGACAGTCGTGATCTTTGACGAAGCTCACAACGTGGAGAA
  GATGTGTGAAGAATCGGCATCCTTTGACCTGACTCCCCATGACCTGGCTTCAGGACTGGACGTCATAGAC
  CAGGTGCTGGAGGAGCAGACCAAGGCAGCGCAGCAGGGTGAGCCCCACCCGGAGTTCAGCGCGGACTCCC
  CCAGCCCAGGGCTGAACATGGAGCTGGAAGACATTGCAAAGCTGAAGATGATCCTGCTGCGCCTGGAGGG
  GGCCATCGATGCTGTTGAGCTGCCTGGAGACGACAGCGGTGTCACCAAGCCAGGGAGCTACATCTTTGAG
  CTGTTTGCTGAAGCCCAGATCACGTTTCAGACCAAGGGCTGCATCCTGGACTCGCTGGACCAGATCATCC
  AGCACCTGGCAGGACGTGCTGGAGTGTTCACCAACACGGCCGGACTGCAGAAGCTGGCGGACATTATCCA
  GATTGTGTTCAGTGTGGACCCCTCCGAGGGCAGCCCTGGTTCCCCAGCAGGGCTGGGGGCCTTACAGTCC
  TATAAGGTGCACATCCATCCTGATGCTGGTCACCGGAGGACGGCTCAGCGGTCTGATGCCTGGAGCACCA
  CTGCAGCCAGAAAGCGAGGGAAGGTGCTGAGCTACTGGTGCTTCAGTCCCGGCCACAGCATGCACGAGCT
  GGTCCGCCAGGGCGTCCGCTCCCTCATCCTTACCAGCGGCACGCTGGCCCCGGTGTCCTCCTTTGCTCTG
  GAGATGCAGATCCCTTTCCCAGTCTGCCTGGAGAACCCACACATCATCGACAAGCACCAGATCTGGGTGG
  GGGTCGTCCCCAGAGGCCCCGATGGAGCCCAGTTGAGCTCCGCGTTTGACAGACGGTTTTCCGAGGAGTG
  CTTATCCTCCCTGGGGAAGGCTCTGGGCAACATCGCCCGCGTGGTGCCCTATGGGCTCCTGATCTTCTTC
  CCTTCCTATCCTGTCATGGAGAAGAGCCTGGAGTTCTGGCGGGCCCGCGACTTGGCCAGGAAGATGGAGG
  CGCTGAAGCCGCTGTTTGTGGAGCCCAGGAGCAAAGGCAGCTTCTCCGAGACCATCAGTGCTTACTATGC
  AAGGGTTGCCGCCCCTGGGTCCACCGGCGCCACCTTCCTGGCGGTCTGCCGGGGCAAGGCCAGCGAGGGG
  CTGGACTTCTCAGACACGAATGGCCGTGGTGTGATTGTCACGGGCCTCCCGTACCCCCCACGCATGGACC
  CCCGGGTTGTCCTCAAGATGCAGTTCCTGGATGAGATGAAGGGCCAGGGTGGGGCTGGGGGCCAGTTCCT
  CTCTGGGCAGGAGTGGTACCGGCAGCAGGCGTCCAGGGCTGTGAACCAGGCCATCGGGCGAGTGATCCGG
  CACCGCCAGGACTACGGAGCTGTCTTCCTCTGTGACCACAGGTTCGCCTTTGCCGACGCAAGAGCCCAAC
  TGCCCTCCTGGGTGCGTCCCCACGTCAGGGTGTATGACAACTTTGGCCATGTCATCCGAGACGTGGCCCA
  GTTCTTCCGTGTTGCCGAGCGAACTATGCCAGCGCCGGCCCCCCGGGCTACAGCACCCAGTGTGCGTGGA
  GAAGATGCTGTCAGCGAGGCCAAGTCGCCTGGCCCCTTCTTCTCCACCAGGAAAGCTAAGAGTCTGGACC
  TGCATGTCCCCAGCCTGAAGCAGAGGTCCTCAGGGTCACCAGCTGCCGGGGACCCCGAGAGTAGCCTGTG
  TGTGGAGTATGAGCAGGAGCCAGTTCCTGCCCGGCAGAGGCCCAGGGGGCTGCTGGCCGCCCTGGAGCAC
  AGCGAACAGCGGGCGGGGAGCCCTGGCGAGGAGCAGGCCCACAGCTGCTCCACCCTGTCCCTCCTGTCTG
  AGAAGAGGCCGGCAGAAGAACCGCGAGGAGGGAGGAAGAAGATCCGGCTGGTCAGCCACCCGGAGGAGCC
  CGTGGCTGGTGCACAGACGGACAGGGCCAAGCTCTTCATGGTGGCCGTGAAGCAGGAGTTGAGCCAAGCC
  AACTTTGCCACCTTCACCCAGGCCCTGCAGGACTACAAGGGTTCCGATGACTTCGCCGCCCTGGCCGCCT
  GTCTCGGCCCCCTCTTTGCTGAGGACCCCAAGAAGCACAACCTGCTCCAAGGCTTCTACCAGTTTGTGCG
  GCCCCACCATAAGCAGCAGTTTGAGGAGGTCTGTATCCAGCTGACAGGACGAGGCTGTGGCTATCGGCCT
  GAGCACAGCATTCCCCGAAGGCAGCGGGCACAGCCGGTCCTGGACCCCACTGGAAGAACGGCGCCGGATC
  CCAAGCTGACCGTGTCCACGGCTGCAGCCCAGCAGCTGGACCCCCAAGAGCACCTGAACCAGGGCAGGCC
  CCACCTGTCGCCCAGGCCACCCCCAACAGGAGACCCTGGCAGCCAACCACAGTGGGGGTCTGGAGTGCCC
  AGAGCAGGGAAGCAGGGCCAGCACGCCGTGAGCGCCTACCTGGCTGATGCCCGCAGGGCCCTGGGGTCCG
  CGGGCTGTAGCCAACTCTTGGCAGCGCTGACAGCCTATAAGCAAGACGACGACCTCGACAAGGTGCTGGC
  TGTGTTGGCCGCCCTGACCACTGCAAAGCCAGAGGACTTCCCCCTGCTGCACAGGTTCAGCATGTTTGTG
  CGTCCACACCACAAGCAGCGCTTCTCACAGACGTGCACAGACCTGACCGGCCGGCCCTACCCGGGCATGG
  AGCCACCGGGACCCCAGGAGGAGAGGCTTGCCGTGCCTCCTGTGCTTACCCACAGGGCTCCCCAACCAGG
  CCCCTCACGGTCCGAGAAGACCGGGAAGACCCAGAGCAAGATCTCGTCCTTCCTTAGACAGAGGCCAGCA
  GGGACTGTGGGGGCGGGCGGTGAGGATGCAGGTCCCAGCCAGTCCTCAGGACCTCCCCACGGGCCTGCAG
  CATCTGAGTGGGGTGAGCCTCATGGGAGAGACATCGCTGGGCAGCAGGCCACGGGAGCTCCGGGCGGGCC
  CCTCTCAGCAGGCTGTGTGTGCCAGGGCTGTGGGGCAGAGGACGTGGTGCCCTTCCAGTGCCCTGCCTGT
  GACTTCCAGCGCTGCCAAGCCTGCTGGCAACGGCACCTTCAGGCCTCTAGGATGTGCCCAGCCTGCCACA
  CCGCCTCCAGGAAGCAGAGCGTCATGCAGGTCTTCTGGCCAGAGCCCCAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001283009
• ORF Size: 3903 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001283009.1, NP_001269938.1
• RefSeq Size: 5140
• RefSeq ORF: 3903
• Locus ID: 51750
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (3) represents the longest transcript and encodes the longest protein (isoform 3).