Human NR0B1 activation kit by CRISPRa

CAT#: GA100134

NR0B1 CRISPRa kit - CRISPR gene activation of human nuclear receptor subfamily 0 group B member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NR0B1
• Locus ID: 190
• Kit Components:

  GA100134G1, NR0B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100134G2, NR0B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100134G3, NR0B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000475
• Synonyms: AHC; AHCH; AHX; DAX-1; DAX1; DSS; GTD; HHG; NROB1; SRXY2
• Summary: 'This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008]'