Human AMELX activation kit by CRISPRa

CAT#: GA100180

AMELX CRISPRa kit - CRISPR gene activation of human amelogenin X-linked

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AMELX
• Locus ID: 265
• Kit Components:

  GA100180G1, AMELX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100180G2, AMELX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100180G3, AMELX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142, NM_182680, NM_182681
• Synonyms: AI1E; AIH1; ALGN; AMG; AMGL; AMGX
• Summary: 'This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]'