Human ATP4B activation kit by CRISPRa

CAT#: GA100350

ATP4B CRISPRa kit - CRISPR gene activation of human ATPase H+/K+ transporting subunit beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ATP4B
• Locus ID: 496
• Kit Components:

  GA100350G1, ATP4B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100350G2, ATP4B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100350G3, ATP4B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000705
• Synonyms: ATP6B
• Summary: The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]