Human BCL9 activation kit by CRISPRa

CAT#: GA100417

BCL9 CRISPRa kit - CRISPR gene activation of human BCL9 transcription coactivator

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BCL9
• Locus ID: 607
• Kit Components:

  GA100417G1, BCL9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100417G2, BCL9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100417G3, BCL9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004326
• Synonyms: LGS
• Summary: 'BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [provided by RefSeq, Jul 2008]'