Human BNC1 activation kit by CRISPRa

CAT#: GA100443

BNC1 CRISPRa kit - CRISPR gene activation of human basonuclin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BNC1
• Locus ID: 646
• Kit Components:

  GA100443G1, BNC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100443G2, BNC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100443G3, BNC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301206, NM_001717, NM_001301206.2
• Synonyms: BNC; BSN1; HsT19447
• Summary: 'This gene encodes a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to play a regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription. Disruption of this gene has been implicated in premature ovarian failure as well as testicular premature aging. [provided by RefSeq, Sep 2020]'