Human CA7 activation kit by CRISPRa

CAT#: GA100533

CA7 CRISPRa kit - CRISPR gene activation of human carbonic anhydrase 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CA7
• Locus ID: 766
• Kit Components:

  GA100533G1, CA7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100533G2, CA7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100533G3, CA7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001014435, NM_005182, NM_001365337
• Synonyms: CAVII
• Summary: 'Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2018]'