Human Calnexin (CANX) activation kit by CRISPRa

CAT#: GA100574

CANX CRISPRa kit - CRISPR gene activation of human calnexin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CANX
• Locus ID: 821
• Kit Components:

  GA100574G1, Calnexin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100574G2, Calnexin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100574G3, Calnexin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001024649, NM_001746, NM_001363996, NM_001364000, NM_001363995, NM_001363997, NM_001363999, NM_001363993, NM_001363994, NM_001363998, NM_001364001, NR_157048
• Synonyms: CNX; IP90; P90
• Summary: 'This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018]'