Human AP2S1 activation kit by CRISPRa

CAT#: GA100838

AP2S1 CRISPRa kit - CRISPR gene activation of human adaptor related protein complex 2 subunit sigma 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AP2S1
• Locus ID: 1175
• Kit Components:

  GA100838G1, AP2S1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100838G2, AP2S1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100838G3, AP2S1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301076, NM_001301078, NM_001301081, NM_004069, NM_021575, NM_001301081.2, NM_001301078.2, NM_001301076.2
• Synonyms: AP17; CLAPS2; FBH3; FBHOk; HHC3
• Summary: 'One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]'