Human CLCA1 activation kit by CRISPRa

CAT#: GA100841

CLCA1 CRISPRa kit - CRISPR gene activation of human chloride channel accessory 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLCA1
• Locus ID: 1179
• Kit Components:

  GA100841G1, CLCA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100841G2, CLCA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100841G3, CLCA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001285
• Synonyms: CACC; CaCC-1; CACC1; CLCRG1; GOB5; hCaCC-1; hCLCA1
• Summary: 'This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq, Jul 2008]'