Human beta COP (COPB1) activation kit by CRISPRa

CAT#: GA100926

COPB1 CRISPRa kit - CRISPR gene activation of human coatomer protein complex subunit beta 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: COPB1
• Locus ID: 1315
• Kit Components:

  GA100926G1, beta COP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100926G2, beta COP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100926G3, beta COP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001144061, NM_001144062, NM_016451
• Synonyms: COPB
• Summary: 'This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]'