Human CKII alpha (CSNK2A1) activation kit by CRISPRa

CAT#: GA101028

CSNK2A1 CRISPRa kit - CRISPR gene activation of human casein kinase 2 alpha 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CSNK2A1
• Locus ID: 1457
• Kit Components:

  GA101028G1, CKII alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101028G2, CKII alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101028G3, CKII alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001895, NM_177559, NM_177560, NM_001362771, NM_001362770
• Synonyms: CK2A1; CKII; CSNK2A3
• Summary: 'Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. Multiple transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Apr 2018]'