Human DHX8 activation kit by CRISPRa

CAT#: GA101171

DHX8 CRISPRa kit - CRISPR gene activation of human DEAH-box helicase 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DHX8
• Locus ID: 1659
• Kit Components:

  GA101171G1, DHX8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101171G2, DHX8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101171G3, DHX8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001302623, NM_001322216, NM_001322217, NM_001322218, NM_001322219, NM_001322220, NM_001322221, NM_004941, NR_136225, NR_136226, NR_136227, NR_136228
• Synonyms: DDX8; HRH1; PRP22; PRPF22
• Summary: 'This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]'