Human XPF (ERCC4) activation kit by CRISPRa

CAT#: GA101449

ERCC4 CRISPRa kit - CRISPR gene activation of human ERCC excision repair 4, endonuclease catalytic subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ERCC4
• Locus ID: 2072
• Kit Components:

  GA101449G1, XPF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101449G2, XPF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101449G3, XPF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005236
• Synonyms: ERCC11; FANCQ; RAD1; XFEPS; XPF
• Summary: 'The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009]'