Human EXT1 activation kit by CRISPRa

CAT#: GA101485

EXT1 CRISPRa kit - CRISPR gene activation of human exostosin glycosyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EXT1
• Locus ID: 2131
• Kit Components:

  GA101485G1, EXT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101485G2, EXT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101485G3, EXT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000127
• Synonyms: EXT; LGCR; LGS; TRPS2; TTV
• Summary: 'This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq, Jul 2008]'