Human CD16b (FCGR3B) activation kit by CRISPRa

CAT#: GA101552

FCGR3B CRISPRa kit - CRISPR gene activation of human Fc fragment of IgG receptor IIIb

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FCGR3B
• Locus ID: 2215
• Kit Components:

  GA101552G1, CD16b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101552G2, CD16b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101552G3, CD16b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000570, NM_001244753, NM_001271035, NM_001271036, NM_001271037
• Synonyms: CD16; CD16b; FCG3; FCGR3; FCR-10; FCRIII; FCRIIIb
• Summary: 'The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]'