Human FDFT1 activation kit by CRISPRa

CAT#: GA101557

FDFT1 CRISPRa kit - CRISPR gene activation of human farnesyl-diphosphate farnesyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FDFT1
• Locus ID: 2222
• Kit Components:

  GA101557G1, FDFT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101557G2, FDFT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101557G3, FDFT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001287742, NM_001287743, NM_001287744, NM_001287745, NM_001287747, NM_001287748, NM_001287749, NM_001287750, NM_001287751, NM_001287756, NM_004462
• Synonyms: DGPT; ERG9; SQS; SS
• Summary: 'This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]'