Human GAB1 activation kit by CRISPRa

CAT#: GA101693

GAB1 CRISPRa kit - CRISPR gene activation of human GRB2 associated binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GAB1
• Locus ID: 2549
• Kit Components:

  GA101693G1, GAB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101693G2, GAB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101693G3, GAB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002039, NM_207123
• Synonyms: GRB2-associated binding protein 1
• Summary: 'The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]'