Human GLO1 activation kit by CRISPRa

CAT#: GA101826

GLO1 CRISPRa kit - CRISPR gene activation of human glyoxalase I

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GLO1
• Locus ID: 2739
• Kit Components:

  GA101826G1, GLO1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101826G2, GLO1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101826G3, GLO1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006708
• Synonyms: GLOD1; GLYI; HEL-S-74
• Summary: 'The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq, Jul 2008]'