Human GPR34 activation kit by CRISPRa

CAT#: GA101918

GPR34 CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor 34

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPR34
• Locus ID: 2857
• Kit Components:

  GA101918G1, GPR34 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101918G2, GPR34 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101918G3, GPR34 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033513, NM_001033514, NM_001097579, NM_005300, N40174
• Synonyms: G protein-coupled receptor 34; OTTHUMP00000023148; OTTHUMP00000023149
• Summary: 'G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM, Apr 2006]'