Human Glycophorin A (GYPA) activation kit by CRISPRa

CAT#: GA102031

GYPA CRISPRa kit - CRISPR gene activation of human glycophorin A (MNS blood group)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GYPA
• Locus ID: 2993
• Kit Components:

  GA102031G1, Glycophorin A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102031G2, Glycophorin A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102031G3, Glycophorin A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001308187, NM_001308190, NM_002099
• Synonyms: CD235a; GPA; GPErik; GPSAT; HGpMiV; HGpMiXI; HGpSta(C); MN; MNS; PAS-2
• Summary: 'Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]'