Human HMX2 activation kit by CRISPRa

CAT#: GA102160

HMX2 CRISPRa kit - CRISPR gene activation of human H6 family homeobox 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HMX2
• Locus ID: 3167
• Kit Components:

  GA102160G1, HMX2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102160G2, HMX2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102160G3, HMX2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005519
• Synonyms: H6L; Nkx5-2
• Summary: 'The protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss. [provided by RefSeq, Aug 2012]'