Human FOXA3 activation kit by CRISPRa

CAT#: GA102163

FOXA3 CRISPRa kit - CRISPR gene activation of human forkhead box A3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FOXA3
• Locus ID: 3171
• Kit Components:

  GA102163G1, FOXA3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102163G2, FOXA3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102163G3, FOXA3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004497
• Synonyms: FKHH3; HNF3G; TCF3G
• Summary: 'This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved. [provided by RefSeq, Jul 2008]'