Human HNF6 (ONECUT1) activation kit by CRISPRa

CAT#: GA102166

ONECUT1 CRISPRa kit - CRISPR gene activation of human one cut homeobox 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ONECUT1
• Locus ID: 3175
• Kit Components:

  GA102166G1, HNF6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102166G2, HNF6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102166G3, HNF6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004498, NR_073510
• Synonyms: HNF-6; HNF6; HNF6A
• Summary: 'This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]'