Human HNRPH1 (HNRNPH1) activation kit by CRISPRa

CAT#: GA102175

HNRNPH1 CRISPRa kit - CRISPR gene activation of human heterogeneous nuclear ribonucleoprotein H1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HNRNPH1
• Locus ID: 3187
• Kit Components:

  GA102175G1, HNRPH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102175G2, HNRPH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102175G3, HNRPH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001257293, NM_005520, NM_001364233, NM_001363572, NM_001364227, NM_001364228, NM_001364234, NM_001364236, NM_001364237, NM_001364239, NM_001364242, NM_001364244, NM_001364245, NM_001364247, NM_001364251, NM_001364252, NM_001364253, NM_001364255, NM_001364225, NM_001364226, NM_001364229, NM_001364230, NM_001364231, NM_001364232, NM_001364235, NM_001364238, NM_001364240, NM_001364241, NM_001364243, NM_001364246, NM_001364248, NM_001364250, NM_001364254
• Synonyms: hnRNPH; HNRPH; HNRPH1
• Summary: 'This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012]'