Human HOXD9 activation kit by CRISPRa

CAT#: GA102217

HOXD9 CRISPRa kit - CRISPR gene activation of human homeobox D9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HOXD9
• Locus ID: 3235
• Kit Components:

  GA102217G1, HOXD9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102217G2, HOXD9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102217G3, HOXD9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014213
• Synonyms: Hox-4.3; Hox-5.2; HOX4; HOX4C
• Summary: 'This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008]'