Human KIR5.1 (KCNJ16) activation kit by CRISPRa

CAT#: GA102548

KCNJ16 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily J member 16

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNJ16
• Locus ID: 3773
• Kit Components:

  GA102548G1, KIR5.1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102548G2, KIR5.1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102548G3, KIR5.1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270422, NM_001291622, NM_001291623, NM_001291624, NM_001291625, NM_018658, NM_170741, NM_170742
• Synonyms: BIR9; KIR5.1
• Summary: 'Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which tends to allow potassium to flow into rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may function in fluid and pH balance regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]'