Human Cytokeratin 18 (KRT18) activation kit by CRISPRa

CAT#: GA102627

KRT18 CRISPRa kit - CRISPR gene activation of human keratin 18

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KRT18
• Locus ID: 3875
• Kit Components:

  GA102627G1, Cytokeratin 18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102627G2, Cytokeratin 18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102627G3, Cytokeratin 18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000224, NM_199187
• Synonyms: CYK18; K18
• Summary: 'KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]'