Human LIMS1 activation kit by CRISPRa
CAT#: GA102701
LIMS1 CRISPRa kit - CRISPR gene activation of human LIM zinc finger domain containing 1
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | LIMS1 |
Locus ID | 3987 |
Kit Components | GA102701G1, LIMS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102701G2, LIMS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102701G3, LIMS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001193482, NM_001193483, NM_001193484, NM_001193485, NM_001193488, NM_004987 |
Synonyms | PINCH; PINCH-1; PINCH1 |
Summary | 'The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]' |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN402765 | LIMS1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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