Human Leucyl cystinyl aminopeptidase (LNPEP) activation kit by CRISPRa

CAT#: GA102719

LNPEP CRISPRa kit - CRISPR gene activation of human leucyl and cystinyl aminopeptidase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LNPEP
• Locus ID: 4012
• Kit Components:

  GA102719G1, Leucyl cystinyl aminopeptidase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102719G2, Leucyl cystinyl aminopeptidase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102719G3, Leucyl cystinyl aminopeptidase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005575, NM_175920
• Synonyms: CAP; IRAP; P-LAP; PLAP
• Summary: 'This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]'