Human MGAT3 activation kit by CRISPRa

CAT#: GA102895

MGAT3 CRISPRa kit - CRISPR gene activation of human mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MGAT3
• Locus ID: 4248
• Kit Components:

  GA102895G1, MGAT3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102895G2, MGAT3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102895G3, MGAT3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001098270, NM_002409
• Synonyms: GNT-III; GNT3
• Summary: 'There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]'