Human Aquaporin 0 (MIP) activation kit by CRISPRa

CAT#: GA102911

MIP CRISPRa kit - CRISPR gene activation of human major intrinsic protein of lens fiber

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MIP
• Locus ID: 4284
• Kit Components:

  GA102911G1, Aquaporin 0 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102911G2, Aquaporin 0 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102911G3, Aquaporin 0 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012064
• Synonyms: AQP0; CTRCT15; LIM1; MIP26; MP26
• Summary: 'Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13. [provided by RefSeq, Jul 2008]'