Human Methionine Sulfoxide Reductase A (MSRA) activation kit by CRISPRa

CAT#: GA102989

MSRA CRISPRa kit - CRISPR gene activation of human methionine sulfoxide reductase A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MSRA
• Locus ID: 4482
• Kit Components:

  GA102989G1, MSRA gRNA vector 1 in pCas-Guide-CRISPRa

  GA102989G2, MSRA gRNA vector 2 in pCas-Guide-CRISPRa

  GA102989G3, MSRA gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135670, NM_001135671, NM_001199729, NM_012331
• Synonyms: PMSR
• Summary: This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]