Human NDUFB2 activation kit by CRISPRa

CAT#: GA103137

NDUFB2 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase subunit B2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NDUFB2
• Locus ID: 4708
• Kit Components:

  GA103137G1, NDUFB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103137G2, NDUFB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103137G3, NDUFB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004546
• Synonyms: AGGG; CI-AGGG
• Summary: 'The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I. [provided by RefSeq, Jul 2008]'