Human PAX4 activation kit by CRISPRa

CAT#: GA103392

PAX4 CRISPRa kit - CRISPR gene activation of human paired box 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PAX4
• Locus ID: 5078
• Kit Components:

  GA103392G1, PAX4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103392G2, PAX4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103392G3, PAX4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006193, NM_001366111, NM_001366110
• Synonyms: KPD; MODY9
• Summary: 'This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells. [provided by RefSeq, Jul 2008]'